Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study.
Ankur Gupta-WrightElizabeth Lucy CorbettDouglas P K WilsonJoep J van OosterhoutKeertan DhedaHelena HuergaJonny PeterMaryline BonnetMelanie Alufandika-MoyoDaniel J GrintStephen D LawnKatherine FieldingPublished in: PLoS medicine (2019)
This risk score is capable of identifying patients who could benefit from enhanced clinical care, follow-up, and/or adjunctive interventions, although further prospective validation studies are necessary. Given the scale of HIV/TB morbidity and mortality in African hospitals, better prognostic tools along with interventions could contribute towards global targets to reduce tuberculosis mortality.
Keyphrases
- hiv aids
- antiretroviral therapy
- mycobacterium tuberculosis
- hiv positive
- healthcare
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- cardiovascular events
- men who have sex with men
- physical activity
- adverse drug
- pulmonary tuberculosis
- palliative care
- risk factors
- quality improvement
- pain management
- type diabetes
- loop mediated isothermal amplification
- cardiovascular disease
- label free
- acute care
- chronic pain
- health insurance