Effects of metformin on knee joint capsule fibrosis in a diabetic mouse model.

Toichiro NaitoYoshiaki YamanakaKotaro TokudaNaohito SatoTakafumi TajimaManabu TsukamotoHitoshi SuzukiMakoto KawasakiEiichiro NakamuraAkinori Sakai

Published in: Bone & joint research (2024)

Hyperglycaemia promotes fibrosis in the mouse knee joint capsule, which is inhibited by metformin. These findings can help inform the development of novel strategies for treating knee joint capsule fibrosis.

Keyphrases

mouse model
type diabetes
wound healing