Low-intensity pulsed ultrasound ameliorates glia-mediated inflammation and neuronal damage in experimental intracerebral hemorrhage conditions.

Wei-Shen SuChun-Hu WuWen-Shin SongSzu-Fu ChenFeng-Yi Yang

Published in: Journal of translational medicine (2023)

LIPUS treatment improved neurological outcomes and reduced glia-mediated inflammation by inhibiting PI3K/Akt-NF-κB signaling after ICH. LIPUS may provide a non-invasive potential management strategy for ICH.

Keyphrases

pi k akt
signaling pathway
oxidative stress
cell cycle arrest
cell proliferation
magnetic resonance imaging
cerebral ischemia
immune response
adipose tissue
computed tomography
risk assessment
climate change
blood brain barrier
lps induced
toll like receptor
human health
inflammatory response
replacement therapy