Clinicoserological features of antisynthetase syndrome (ASyS)-associated interstitial lung disease presenting to respiratory services: comparison with idiopathic pulmonary fibrosis and ASyS diagnosed in rheumatology services.
Shaney Louise BarrattHavra H AdamaliCaroline CottonBen MulhearnHina IftikharJohn David PaulingLisa SpencerHuzaifa I AdamaliHarsha GunawardenaPublished in: BMJ open respiratory research (2021)
Extended autoimmune serology is needed to evaluate for ASyS autoantibodies in patients presenting with ILD, particularly in younger female patients. Musculoskeletal involvement is common in ASyS (typically Jo-1 autoantibodies) presenting to rheumatology but the burden of ILD is similar to those presenting to respiratory medicine.
Keyphrases
- interstitial lung disease
- idiopathic pulmonary fibrosis
- systemic sclerosis
- case report
- rheumatoid arthritis
- healthcare
- primary care
- end stage renal disease
- systemic lupus erythematosus
- ejection fraction
- newly diagnosed
- mental health
- chronic kidney disease
- prognostic factors
- multiple sclerosis
- patient reported outcomes
- drug induced
- patient reported