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Effect of CYP3A4 Induction and Inhibition on the Pharmacokinetics of SHR0302 in Healthy Subjects.

Zhe ZhangXuehu GaoPing ZhangYuan LiMeng FuHongda LinSheng FengKai ShenGuoning YuXin Li
Published in: British journal of clinical pharmacology (2023)
Strong CYP3A4 induction and inhibition both resulted in a weak effect on the clinical exposures of SHR0302. These present studies provided valuable information that help inform SHR0302 dosing instructions and concomitant medication precautions.
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