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Enhancing backcross programs through increased recombination.

Elise TourretteMatthieu FalqueOlivier C Martin
Published in: Genetics, selection, evolution : GSE (2021)
Depending on the recombination rate in the region targeted for introgression, increasing it can be beneficial or detrimental. Thus, the simulations analysed in this paper help us understand how an increase in recombination rate can be beneficial. They also highlight the best methods that can be used to increase recombination rate, depending on the situation.
Keyphrases
  • dna repair
  • dna damage
  • public health
  • cancer therapy