Novel Adiponectin Receptor Agonist Inhibits Cholangiocarcinoma via Adenosine Monophosphate-activated Protein Kinase.
Khac Cuong BuiThi Mai Ly NguyenSamarpita BaratTim ScholtaJun XingVikas BhuriaBence SiposLudwig WilkensLinh Toan NguyenHuu Song LeThirumalaisamy P VelavanPrzemyslaw BozkoRuben R PlentzPublished in: Current medicinal chemistry (2024)
AdipoR1 and p-AMPKα are impaired in CCA tissues, and AdipoRon effectively inhibits CCA in vitro and in vivo. Thus, AdipoRon may be considered as a potential anti-tumor therapy in CCA.