The Potential Role of Persister Cells in Urinary Tract Infections.
Butool DurraniAshu MohammadBernardita M LjubeticAmy Diane DobberfuhlPublished in: Current urology reports (2023)
This review summarizes recent research on the pathogenesis of persister cell formation in UTIs, the impact of persister cells on the effectiveness of antibiotics, the challenges they pose for treatment, and the need for new strategies to target these cells. Furthermore, this review examines the current state of research on the identification and characterization of persister cells in UTIs, as well as the future directions for investigations in this field. This review highlights the importance of understanding the role of persister cells in UTIs and the potential impact of targeting these cells in the development of new treatments.