Multimodal analysis using [11C]PiB-PET/MRI for functional evaluation of patients with Alzheimer's disease.
Hidehiko OkazawaMasamichi IkawaMinyoung JungRikiya MaruyamaTetsuya TsujikawaTetsuya MoriMahmudur G M RahmanAkira MakinoYasushi KiyonoHirotaka KosakaPublished in: EJNMMI research (2020)
Multimodal analysis conducted with various image data from PiB-PET/MRI scans showed differences in regional CBF, cortical volume, and neuronal networks in different regions, indicating that pathophysiologic and functional changes in the AD brain can be observed from various aspects of neurophysiologic parameters. Application of multimodal brain images using PET/MRI would be ideal for investigating pathophysiologic changes in patients with dementia and other neurodegenerative diseases.
Keyphrases
- contrast enhanced
- pet imaging
- computed tomography
- magnetic resonance imaging
- positron emission tomography
- pet ct
- pain management
- deep learning
- diffusion weighted imaging
- white matter
- resting state
- cerebral ischemia
- magnetic resonance
- mild cognitive impairment
- electronic health record
- optical coherence tomography
- multiple sclerosis
- machine learning
- brain injury
- artificial intelligence
- data analysis