Methylated ctDNA predicts early recurrence risk in patients undergoing resection of initially unresectable colorectal cancer liver metastases.

Zhi-Gang ChenXiao-Meng JiYu-Xia XuWilliam Pat FongXiao-Yun LiuJie-Ying LiangQiong TanLei WenYan-Yu CaiDe-Sheng Wang Yu-Hong Li

Published in: Therapeutic advances in medical oncology (2024)

Our study confirmed that serial ctDNA analysis of NPY and SEPT9 gene methylation could effectively predict early recurrence in IU-CRLM patients, especially at POST and EOT.

Keyphrases

liver metastases
patients undergoing
end stage renal disease
ejection fraction
newly diagnosed
genome wide
chronic kidney disease
peritoneal dialysis
dna methylation
free survival
prognostic factors
circulating tumor
gene expression
radiation therapy
patient reported
transcription factor