Immune Phenotype and Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer.
Clinton YamEr-Yen YenJeffrey T ChangRoland L BassettGheath AlatrashHaven R GarberLei HuoFei YangAnne V PhilipsQing-Qing DingBora LimNaoto Tada UenoKasthuri KannanXiangjie SunBaohua SunEdwin Roger Parra CuentesWilliam Fraser SymmansJason B WhiteElizabeth RavenbergSahil B SethJennifer L GuerrieroGaiane M RauchSenthil DamodaranJennifer K LittonJennifer A WargoGabriel N HortobagyiAndrew FutrealIgnacio I WistubaRyan SunStacy L MoulderElizabeth A MittendorfPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
In patients receiving NAT for TNBC, deep immune profiling through detailed phenotypic characterization and spatial analysis can improve prediction of pCR in patients receiving NAT for TNBC when considered with traditional clinical parameters.