Soluble ST2 as a New Oxidative Stress and Inflammation Marker in Metabolic Syndrome.
Ignacio RoyEva JoverLara MatillaVirginia AlvarezAmaya Fernández-CelisMaite BeunzaElena EscribanoAlicia GainzaRafael SadabaNatalia Lopez-AndreésPublished in: International journal of environmental research and public health (2023)
Circulating levels of sST2 are associated with oxidative stress and inflammation burden and may underlie the pathological remodeling and dysfunction of the heart in MS patients. Our results suggest that sST2 elevation precedes diastolic dysfunction, emerging as an attractive biotarget in MS.
Keyphrases
- oxidative stress
- metabolic syndrome
- dna damage
- diabetic rats
- ejection fraction
- mass spectrometry
- ischemia reperfusion injury
- multiple sclerosis
- induced apoptosis
- end stage renal disease
- ms ms
- newly diagnosed
- blood pressure
- heart failure
- left ventricular
- prognostic factors
- cardiovascular disease
- type diabetes
- insulin resistance
- heat shock
- peritoneal dialysis
- risk factors
- adipose tissue
- atrial fibrillation
- cardiovascular risk factors
- endoplasmic reticulum stress