Brain uptake and distribution patterns of 2-hydroxypropyl-ß-cyclodextrin after intrathecal and intranasal administration.

William A BanksPericles CaliasKim M HansenKristin M BullockKory Engelke

Published in: The Journal of pharmacy and pharmacology (2022)

Kleptose was taken up by all regions of the CNS after either IN or IT administration, but IN administration resulted in only a fraction of the uptake of the IT route.

Keyphrases

resting state
white matter
mass spectrometry
functional connectivity
brain injury
capillary electrophoresis