Site-Specific Photoaffinity Bioconjugation for the Creation of 89 Zr-Labeled Radioimmunoconjugates.

-huA33) boasted high specific activity, stability, and immunoreactivity. While the site-specifically modified radioimmunoconjugate produced high activity concentrations in tumor tissue, it also yielded higher uptake in healthy organs than a stochastically modified analog, suggesting that optimization of this system is necessary prior to clinical translation.