Identification of Novel Tumor Pyroptosis-Related Antigens and Pyroptosis Subtypes for Developing mRNA Vaccines in Pancreatic Adenocarcinoma.

Qiaowei LinLi LiangQing WangXiao WangYang YouYefei RongYuhong ZhouXi Guo

Published in: Biomedicines (2024)

are prospective pyroptosis-related antigens for mRNA vaccine development, which holds potential benefits for patients classified as PS3 and those with diminished hub gene expressions, providing insights into personalized mRNA vaccine strategies.

Keyphrases

nlrp inflammasome
end stage renal disease
newly diagnosed
binding protein
ejection fraction
chronic kidney disease
dendritic cells
peritoneal dialysis
prognostic factors
genome wide
gene expression
immune response
patient reported outcomes
transcription factor
drug induced
network analysis