Amyloid fibrils from organic solutions of an amphiphilic dipeptide.
Jordi CasanovasEnric MayansAngélica DíazAna M GilAna I JiménezCarlos CativielaJordi PuiggalíCarlos AlemánPublished in: Chemical communications (Cambridge, England) (2019)
Non-hydrated organic solutions of a diphenylalanine amphiphile blocked at the C-terminus with a fluorenylmethyl ester and stabilized at the N-terminus with a trifluoroacetate have been used to prepare amyloid fibrils. The solvent used to prepare the stock solution together with the co-solvent added enables regulation of the characteristics of the fibrils, which is important for their use in technological applications.
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