AT1-AA Is Produced in Offspring in Response to Placental Ischemia and Is Lowered by B-Cell Depletion Without Compromising Overall Offspring Health.
Nathan CampbellEvangeline M DeerDylan SoliseDenise C CorneliusTy TurnerLorena M AmaralOwen HerrockAriel JordanShivani ShuklaTarek IbrahimBabbette B LaMarcaPublished in: Journal of the American Heart Association (2024)
Our findings indicate that perinatal rituximab lowers maternal mean arterial pressure in RUPP rats and improves birth weight, circulating AT1-AA, and circulating natural killer cells, indicating that rituximab improves adverse fetal outcomes in response to placental ischemia.
Keyphrases
- birth weight
- natural killer cells
- gestational age
- weight gain
- diffuse large b cell lymphoma
- high fat diet
- healthcare
- public health
- chronic lymphocytic leukemia
- hodgkin lymphoma
- pregnant women
- mental health
- preterm birth
- health information
- type diabetes
- adipose tissue
- social media
- emergency department
- physical activity
- adverse drug
- electronic health record