Combined Effects of Focused Ultrasound and Photodynamic Treatment for Malignant Brain Tumors Using C6 Glioma Rat Model.

Junwon Park Chanho Kong Jaewoo Shin Ji Young Park Young Cheol Na Seung Hee Han Jin Woo Chang Seung Hyun Song Won Seok Chang

Published in: Yonsei medical journal (2023)

Our findings show that light with sensitizers can inhibit GBM growth, but not ultrasound. Although SPDT did not show the combined effect in MRI, high oxidative stress was observed in IHC. Further studies are needed to investigate the safety parameters to apply ultrasound in GBM.

Keyphrases

magnetic resonance imaging
oxidative stress
contrast enhanced
contrast enhanced ultrasound
ultrasound guided
dna damage
magnetic resonance
cancer therapy
induced apoptosis
replacement therapy
solar cells
signaling pathway
diffusion weighted imaging
endoplasmic reticulum stress