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Assessment of genome annotation using gene function similarity within the gene neighborhood.

Se-Ran JunIntawat NookaewLoren HauserAndrey Gorin
Published in: BMC bioinformatics (2017)
Our model clearly distinguished true annotation from random annotation with Bayesian annotation probability >0.95. Our model will provide a useful guide to quantitatively evaluate functional annotation methods and to detect gene sets with reliable annotations.
Keyphrases
  • rna seq
  • genome wide
  • copy number
  • genome wide identification
  • single cell
  • physical activity