Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury.

Johannes Maximilian Ludwig Yuling ZhangWalee ChamulitratWolfgang StremmelAnita Pathil

Published in: PloS one (2018)

In the setting of endotoxin-mediated liver inflammation, UDCA-LPE exerts profound anti-inflammatory and anti-fibrotic effect implying a promising potential for the drug candidate as an experimental approach for the treatment of acute and chronic liver diseases.

Keyphrases

drug induced
liver injury
anti inflammatory
oxidative stress
adverse drug
liver failure
systemic sclerosis
intellectual disability
emergency department
respiratory failure
combination therapy
replacement therapy