PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer.
Katherine D GrayJaclyn E McCloskeyYogindra VedvyasOlivia R KallooSteve El EshakyYanping YangEnda ShevlinMarjan ZamanTimothy M UllmannHeng LiangDessislava StefanovaPaul J ChristosTheresa ScognamiglioAndrew B TasslerRasa ZarnegarThomas J FaheyMoonsoo M JinIrene M MinPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Targeting two IFNγ-inducible, tumor-associated antigens-ICAM1 and PD-L1-in a complementary manner might be an effective treatment strategy to control advanced thyroid cancers in vivo.