Durability of SARS-CoV-2-specific T cell responses at 12-months post-infection.
Zhongyan LuEric D LaingJarina Pena DaMataKatherine PohidaMarana S TsoEmily C SamuelsNusrat J EpsiBatsukh DorjbalCamille LakeStephanie A RichardRyan C MavesDavid A LindholmJulia RozmanCaroline EnglishNikhil HuprikarKatrin MendeRhonda E ColomboChristopher J ColomboChristopher C BroderAnuradha GanesanCharlotte A LanteriBrian K AganDavid TribbleMark P SimonsClifton L DalgardPaul W BlairJosh ChenowethSimon D PollettAndrew L SnowTimothy H BurgessAllison M W Malloynull nullPublished in: The Journal of infectious diseases (2021)
Our data show that SARS-CoV-2 infection induces polyfunctional memory T cells detectable at 12-months post-infection, with higher frequency noted in those who originally experienced severe disease.