PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation.
Farjana SaiadaKun ZhangRenfeng LiPublished in: Cell & bioscience (2021)
Our study reveals that PIAS1 synergizes with SAMHD1 to inhibit EBV lytic replication through protein-protein interaction and SUMOylation.