Clinical and imaging features of women with polygenic partial lipodystrophy: a case series.

Wann Jia LohJadegoud YaligarAmanda J HooperSuresh Anand SadananthanYeshe KwaySu Chi LimGerald F WattsSambasivam Sendhil VelanMelvin Khee-Shing LeowJoan Khoo

Published in: Nutrition & diabetes (2024)

Women with FPLD1 in Singapore have significant loss of adipose but not muscle tissue in lower limbs and have early onset of diabetes. Reduced thigh skinfold, and increased ratio of trunk to leg fat percentage on DXA are potentially clinically useful markers to identify FPLD1.

Keyphrases

early onset
late onset
adipose tissue
type diabetes
high resolution
cardiovascular disease
body composition
skeletal muscle
insulin resistance
glycemic control
bone mineral density
lower limb
soft tissue
magnetic resonance imaging