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Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders.

Julie ChowMatthew JensenHajar AminiFarhad HormozdiariOsnat PennSagiv ShifmanSanthosh GirirajanFereydoun Hormozdiari
Published in: Genome medicine (2019)
In summary, our method identifies modules enriched with de novo non-synonymous mutations and can capture specific networks that underlie the epilepsy phenotype and display distinct enrichment in relevant biological processes. MAGI-S is available at https://github.com/jchow32/magi-s .
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • temporal lobe epilepsy
  • gene expression
  • congenital heart disease