Anticoagulation and Bleeding during Veno-Venous Extracorporeal Membrane Oxygenation: Insights from the PROTECMO Study.

Gennaro MartucciMarco GianiMatthieu SchmidtKenichi TanakaAli TabatabaiFabio TuzzolinoCara AgerstrandJordi RieraRaj RamananGiacomo GrasselliAli Ait HssainWhitney D GannonSara BuabbasVojka GorjupBrian TrethowanMonica RizzoVito FanelliKyeongman JeonGennaro De PascaleAlain CombesMarco V RanieriThibault DuburcqGiuseppe FotiJuan I ChicoMartin BalikLars Mikael BromanPeter SchellongowskiHergen BuscherRoberto LorussoDaniel BrodieAntonio Arcadipanenull null

Published in: American journal of respiratory and critical care medicine (2023)

Anticoagulation during VV ECMO was a dynamic process, with frequent stopping in cases of bleeding, and restart according to the clinical picture. Future studies might explore lower aPTT targets to reduce the risk of bleeding.

Keyphrases

extracorporeal membrane oxygenation
atrial fibrillation
acute respiratory distress syndrome
respiratory failure
venous thromboembolism
mechanical ventilation