Integration of RNA-Seq data with heterogeneous microarray data for breast cancer profiling.
Daniel CastilloJuan Manuel GálvezLuis Javier HerreraBelén San RománFernando RojasIgnacio RojasPublished in: BMC bioinformatics (2017)
This work proposes a novel data integration stage in the traditional gene expression analysis pipeline through the combination of heterogeneous data from microarrays and RNA-Seq technologies. Available samples have been successfully classified using a subset of six genes obtained by a feature selection method. Consequently, a new classification and diagnosis tool was built and its performance was validated using previously unseen samples.