Papillary Thyroid Carcinoma: Correlation Between Molecular and Clinical Features.
Qiang WangBo YuShuilong ZhangDongliang WangZhifu XiaoHongjing MengLingxiang DongYuhang ZhangJie WuZebin HouYunji ZhuDewei LiPublished in: Molecular diagnosis & therapy (2024)
This study uncovered several significant insights. Younger PTC patients exhibited a higher propensity for lymph node metastasis. An elevated mutation frequency of BRAF was correlated with a higher occurrence of RET fusions, predisposing individuals to lymph node metastasis and potentially indicating a poorer prognosis.