Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia.

Emmanuel Jean-Marie Mignot Richard K BoganHelene EmsellemNancy Foldvary-SchaeferMelissa NaylorRachel NeuwirthHélène FaesselTodd SwickTina Olsson

Published in: Sleep (2023)

A single infusion of danavorexton improves subjective and objective excessive daytime sleepiness in people with IH with no serious TEAEs, indicating orexin-2 receptor agonists are promising treatments for IH.

Keyphrases

sleep quality
obstructive sleep apnea
low dose
positive airway pressure
physical activity
weight gain