A new hypothesis to investigate bioequivalence of pharmaceutical inhalation products.

Maryam KhoubnasabjafariElaheh RahimpourMorteza SaminiVahid Jouyban-GharamalekiLan ChenDonghao ChenHak-Kim ChanAbolghasem Jouyban

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2019)

The methods based on EBC analysis can potentially be applied to bioequivalence study of inhalation products and could reflect drug concentration in ALF. However, experimental studies would be necessary to support or refute this hypothesis on the novel application of EBC to bioequivalence in the future. Graphical abstract In vitro (cascade impactor) and In vivo (EBC concentration) corrolation for inhaled drugs.

Keyphrases

cystic fibrosis
current status
emergency department
drug induced
case control