The mucin protein MUCL1 regulates melanogenesis and melanoma genes in a manner dependent on threonine content.

Published in: The British journal of dermatology (2021)

We identified a significant association between MUCL1 and threonine with melanogenesis and metastasis-related genes in melanoma cells. Our results define a novel mechanism of mucin regulation, suggesting diagnostic and preventive roles of MUCL1 in cutaneous melanoma.

Keyphrases

protein kinase
skin cancer
genome wide
basal cell carcinoma
protein protein
binding protein
amino acid
dna methylation
small molecule