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Potential antidiabetic activity of benzimidazole derivative albendazole and lansoprazole drugs in different doses in experimental type 2 diabetic rats

Burak DikDevran CoşkunEmre BahçivanKamil Uney
Published in: Turkish journal of medical sciences (2021)
The lansoprazole and albendazole treatments can be a potential drug or combined with antidiabetic drugs in T2D treatment by Adenosine 5′-monophosphate activated protein kinase (AMPK), peroxisome proliferator-activated receptor (PPAR), incretin-like effect and other antidiabetic mechanisms. It may be beneficial to create an effective treatment strategy by developing more specific substances with benzimidazole scaffold.
Keyphrases
  • protein kinase
  • diabetic rats
  • oxidative stress
  • molecular docking
  • type diabetes
  • insulin resistance
  • risk assessment
  • drug induced
  • metabolic syndrome
  • human health
  • adipose tissue
  • combination therapy