Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis.
Ivan L SalazarAna S T LourençoBruno ManadasInês BaldeirasCláudia FerreiraAnabela Claro TeixeiraVera M MendesAna Margarida NovoRita MachadoSónia BatistaMaria do Carmo MacárioMário GrãosLívia SousaMaria João SaraivaAlberto A C C PaisCarlos B DuartePublished in: Journal of neuroinflammation (2022)
The model built based on the results obtained upon analysis of the 2D-gels and in the validation phase attained an accuracy of about 80% in distinguishing multiple sclerosis patients and the other two groups.