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Beyond the Heartbeat: Single-Cell Omics Redefining Cardiovascular Research.

Sabine SeelerKristjan ArnarssonMartina DreßenMarkus KraneStefanie A Doppler
Published in: Current cardiology reports (2024)
Recent strides in single-cell omics technologies have revolutionized our understanding of the heart's cellular composition, cell type heterogeneity, and molecular dynamics. These advancements have elucidated pathological conditions as well as the cellular landscape in heart development. We highlight emerging applications of integrated single-cell omics, particularly for cardiac regeneration, disease modeling, and precision medicine, and emphasize the transformative potential of these technologies to advance cardiovascular research and clinical practice.
Keyphrases
  • single cell
  • molecular dynamics
  • rna seq
  • high throughput
  • clinical practice
  • heart failure
  • density functional theory
  • stem cells
  • atrial fibrillation
  • left ventricular
  • risk assessment