A Life Course Approach to the Relationship Between Fetal Growth and Hypothalamic-Pituitary-Adrenal Axis Function.

Wrivu N Martin Carol A WangStephen J LyeStephen G MatthewsRebecca M ReynoldsCarly E McLaughlinRoger Smith Craig E Pennell

Published in: The Journal of clinical endocrinology and metabolism (2021)

We observed an inverse linear relationship between fetal growth and HPA-A function at age 18 years. This differs from the inverse parabolic relationship (inverted U curve) reported in adults of advanced age. Altered adrenal sensitivity may underlie this relationship.

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