The Potential of Digital Polymerase Chain Reaction for Improving Diagnostic Yield of Nontuberculous Mycobacteria Pulmonary Disease.
Yoichi NishiiKazuki FuruhashiSaki NakamuraMiho NishioYuki NakamuraKengo UshiroKentaro ItoTadashi SakaguchiYuta SuzukiKentaro FujiwaraTaro YasumaTetsu KobayashiCorina D'Alessandro-GabazzaEsteban C GabazzaOsamu TaguchiOsamu HatajiPublished in: Infection and drug resistance (2021)
Digital PCR analysis of nontuberculous mycobacteria in bronchial lavage fluid shows a high concordance rate with the bronchial lavage fluid culture results and a high positive predictive value using both sputum and saliva, suggesting the potential usefulness of dPCR for diagnosis of nontuberculous mycobacteria pulmonary disease in clinical practice.