Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers.
Anaïs Jiménez-ReinosoNéstor TiradoAlba Martinez-MorenoVíctor M DiazMarina García-PeydróOana HangiuLaura Díez-AlonsoÁngela AlbitrePetronila PenelaMaría Luisa ToribioPablo MenéndezLuis Alvarez-VallinaDiego Sánchez-MartínezPublished in: Journal for immunotherapy of cancer (2022)
Our data suggest that CD1a-STAb T cells could be an alternative to CD1a-CAR T cells in coT-ALL patients with aggressive and hyperleukocytic relapses with limited numbers of non-leukemic effector T cells.