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Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.

Zhehao ShiZhiming LiBin JinWen YeLuhui WangSina ZhangJiuyi ZhengZixia LinBo ChenFangting LiuBaofu ZhangXiwei DingZhen YangYunfeng ShanZhengping YuYi WangJicai ChenQiang ChenLewis R RobertsGang Chen
Published in: Clinical and translational medicine (2023)
Our findings suggest that a novel translational strategy combining sorafenib with DUXAP8 silencing to overcome drug resistance may improve treatment efficacy in patients with advanced HCC.
Keyphrases
  • diabetic rats
  • high glucose
  • long non coding rna
  • combination therapy