Potential therapeutic target identification in the novel 2019 coronavirus: insight from homology modeling and blind docking study.

Olanrewaju Ayodeji DurojayeTalifhani MushianaHenrietta Onyinye UzoetoSamuel CosmasVictor Malachy UdowoAbayomi Gaius OsotuyiGlory Omini IbiangMiapeh Kous Gonlepa

Published in: The Egyptian journal of medical human genetics (2020)

In line with results from this study which has shown great consistency with other scientific findings on coronaviruses, we recommend the administration of the selected HIV protease inhibitors as first-line therapeutic agents for the treatment of the current coronavirus epidemic.

Keyphrases

sars cov
human immunodeficiency virus
antiretroviral therapy
hepatitis c virus
molecular dynamics simulations
climate change
hiv testing
small molecule
south africa
combination therapy
smoking cessation
replacement therapy
respiratory syndrome coronavirus