Evidence of Residual Ongoing Viral Replication in Chronic Hepatitis B Patients Successfully Treated With Nucleos(t)ide Analogues.

Tong YuMiaoqu ZhangHanyue ZhangJianming ZhengChuan ShenNing JiangLei ZouJing WangYiqi YuQiran ZhangShuili YuYanfang HuangYuxian HuangJi-Ming ZhangChao QiuWenhong ZhangZhefeng Meng

Published in: The Journal of infectious diseases (2023)

We conclude that even after prolonged treatment, a small proportion of the cccDNA reservoir is constantly replenished by continued low-level HBV replication, whereas a large proportion of the cccDNA reservoir persists over time.

Keyphrases

hepatitis b virus
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
sars cov
peritoneal dialysis
prognostic factors
molecular docking
water quality
patient reported outcomes
liver failure
combination therapy
patient reported