Distinct Mechanisms of Cytotoxicity in Novel Nitrogenous Heterocycles: Future Directions for a New Anti-Cancer Agent.

Rasha Saad Suliman Sahar Saleh Alghamdi Rizwan AliIshrat RahmanTariq AlqahtaniIbrahim K FrahDimah A AljatliSarah HuwaiziShatha AlgheribeZeyad I Alehaideb Imadul Islam

Published in: Molecules (Basel, Switzerland) (2022)

The imidazole derivative compound 9 is a promising anti-cancer agent that switches on caspase-dependent apoptotic cell death and modulates microtubule function. Therefore, it could be a lead compound for further drug optimization and development.

Keyphrases

cell death
cell cycle arrest
current status
adverse drug
oxidative stress
emergency department
electronic health record