Bacterial and Viral Infection and Sepsis in Kidney Transplanted Patients.
Alberto MellaFilippo MarianoCaterina DollaEster GalloAna Maria ManzioneMaria Cristina Di VicoRossana CavalloFrancesco Giuseppe De RosaCristina CostaLuigi BianconePublished in: Biomedicines (2022)
Kidney transplanted patients are a unique population with intrinsic susceptibility to viral and bacterial infections, mainly (but not exclusively) due to continuous immunosuppression. In this setting, infectious episodes remain among the most important causes of death, with different risks according to the degree of immunosuppression, time after transplantation, type of infection, and patient conditions. Prevention, early diagnosis, and appropriate therapy are the goals of infective management, taking into account that some specific characteristics of transplanted patients may cause a delay (the absence of fever or inflammatory symptoms, the negativity of serological tests commonly adopted for the general population, or the atypical anatomical presentation depending on the surgical site and graft implantation). This review considers the recent available findings of the most common viral and bacterial infection in kidney transplanted patients and explores risk factors and outcomes in septic evolution.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- type diabetes
- sars cov
- stem cells
- acute kidney injury
- patient reported outcomes
- metabolic syndrome
- public health
- depressive symptoms
- adipose tissue
- cell therapy
- insulin resistance
- smoking cessation
- septic shock
- patient reported