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Synthetic Route to Oscillatoxin D and Its Analogues.

Yoshihiko NokuraYusuke ArakiAtsuo NakazakiToshio Nishikawa
Published in: Organic letters (2018)
O-Methyloscillatoxin D and its analogues were concisely synthesized by a bioinspired intramolecular Mukaiyama aldol reaction as a key step, which involves the construction of a novel spiro-ether moiety.
Keyphrases
  • molecular docking
  • structure activity relationship
  • molecular dynamics simulations
  • energy transfer