Increased platelet activation and lower platelet-monocyte aggregates in COVID-19 patients with severe pneumonia.

Sirada SrihirunThanaporn SriwantanaSirawat SrichatrapimukPornpun VivithanapornSuppachok KirdlarpSomnuek SungkanuparphSithakom PhusantiNithita NanthatantiPrasit SuwannalertNathawut Sibmooh

Published in: PloS one (2023)

COVID-19 patients have higher platelet-leukocyte aggregates and P-selectin expression than controls, indicating increased platelet activation. Compared within patient groups, platelet-monocyte aggregates were lower in severe pneumonia patients.

Keyphrases

sars cov
end stage renal disease
dendritic cells
peripheral blood
ejection fraction
chronic kidney disease
newly diagnosed
early onset
prognostic factors
binding protein
patient reported outcomes