A new approach to produce [18F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function.

Lara Garcia-VarelaKhaled AttiaJohn Carlo SembranoOlivier JacquetInês F AntunesChantal KwizeraTon J VisserRudi A J O DierckxPhilip H ElsingaGert Luurtsema

Published in: EJNMMI radiopharmacy and chemistry (2021)

[18F]MC225 was successfully produced via a 1-step reaction. The procedure is suitable for automation using commercially available synthesis modules. The automation of the radiosynthesis in the Synthera module allows the production of the [18F]MC225 by a reliable and simple method.

Keyphrases

pet imaging
computed tomography
positron emission tomography
minimally invasive
pet ct