Usefulness of saliva for perampanel therapeutic drug monitoring.
Do-Yong KimJangsup MoonYong-Won ShinSoon Tae LeeKeun Hwa JungKyung-Il ParkKi-Young JungManho KimSeungHwan LeeKyung-Sang YuIn-Jin JangKaHeon SongKon ChuSang Kun LeePublished in: Epilepsia (2020)
The PER concentration in saliva was correlated with that in plasma. This correlation was not affected by CYP3A4 inducers. Our results demonstrate for the first time that PER is measurable in saliva and suggest the potential for the clinical application of the saliva PER TDM matrix.
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