Brain-derived neurotrophic factor in diabetes mellitus: A systematic review and meta-analysis.

Fatemeh MoosaieSoheil MohammadiAmene SaghazadehFatemeh Dehghani FirouzabadiNima Rezaei

Published in: PloS one (2023)

Serum BDNF levels were lower in patients with DM, T2DM, DM with depression, and DM and DR than the controls. Our findings are in line with the hypothesis that decreased BDNF levels might impair glucose metabolism and contribute to the pathogenesis of DM and its complications.

Keyphrases

glycemic control
type diabetes
depressive symptoms
stress induced
metabolic syndrome
skeletal muscle
insulin resistance