Neonatal Outcomes after Combined Opioid and Nicotine Exposure in Utero: A Scoping Review.

Krystyna R IsaacsSravanthi Atreyapurapu Amal H AlyusufDavid M LedgerwoodLoretta P FinneganKatie H K ChangTony Xuyen Ma Yukiko Washio

Published in: International journal of environmental research and public health (2021)

The combined exposure to nicotine and opioids during pregnancy may lead to a reduction in neonatal birth weight and birth length and more severe NAS signs, compared with opioid use alone, but more research is necessary to identify the minimum dosage and length of nicotine exposure to accurately predict these outcomes.

Keyphrases

birth weight
gestational age
smoking cessation
chronic pain
pain management
weight gain
preterm birth
early onset
type diabetes
body mass index
skeletal muscle
adipose tissue
insulin resistance