Dose-dependent effects of PRC2 and HDAC inhibitors on cardiomyocyte hypertrophy induced by phenylephrine.
Zhenyi ZhaoJian LvNingning GuoQiuxiao GuoSai ZengYu FangWeixin ChenZhihua Wang
Published in: Current drug targets (2023)
Our data demonstrate diversified effects of TSA and GSK126 on PE-induced cardiomyocyte hypertrophy, and shed light on epigenetic reprogramming in the pathogenesis of cardiac hypertrophy.