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Skin biopsy reveals generalized small fibre neuropathy in hypermobile Ehlers-Danlos syndromes.

Denver IgharoJoana C ThielRoman RolkeMerve AkkayaJoachim WeisIstvan KatonaJörg B SchulzAndrea B Maier
Published in: European journal of neurology (2022)
These results confirm histologically proven SFN as a common feature in patients with hEDS revealing a generalized distribution of nerve fibre loss. Regarding the frequently reported autonomic and neuropathic dysfunctions, the findings support SFN as an important, but not the only, underlying pathomechanism.
Keyphrases
  • heart rate variability
  • machine learning
  • heart rate
  • ultrasound guided
  • soft tissue
  • deep learning
  • wound healing
  • peripheral nerve
  • neural network